If you’re craving a comforting, creamy, and savory meal, this Chicken and Spinach Casserole with Cream Cheese will quickly become your go-to recipe. Packed with tender chicken, fresh spinach, and a decadent cream cheese sauce, this casserole is a deliciously satisfying dinner option for the whole family. With just a few simple ingredients, this dish is incredibly easy to prepare and guarantees a flavorful and hearty meal. Whether you’re in need of a weeknight dinner or something special for a gathering, this casserole checks all the boxes for taste, convenience, and nutrition. It’s the perfect balance of creamy and savory, making it an irresistible option for any occasion.

Why You’ll Love This Recipe

1. Creamy and Flavorful

The cream cheese and sour cream mixture gives this casserole a rich and smooth texture that pairs perfectly with the tender chicken and spinach.

2. Easy to Make

With minimal prep time and simple ingredients, this casserole comes together quickly, allowing you to enjoy a home-cooked meal without a lot of fuss.

3. One-Pot Dish

It’s baked all in one dish, making cleanup a breeze. Simply layer, bake, and enjoy!

4. Packed with Nutrients

Fresh spinach adds a healthy dose of vitamins and minerals, making this dish as nutritious as it is tasty.

5. Perfect for Meal Prep

This casserole can be easily made ahead of time and stored for later, making it a great option for busy days.

Ingredients

For the Casserole

Boneless, skinless chicken breasts
Fresh spinach
Cream cheese (softened)
Sour cream
Garlic cloves
Shredded mozzarella cheese
Salt
Black pepper
Paprika
Onion powder
Olive oil

Variations

Add Veggies: You can add other vegetables like mushrooms, bell peppers, or zucchini to the casserole for extra flavor and nutrition.
Use Different Cheese: If you prefer a different cheese, try substituting the mozzarella with cheddar or Parmesan for a unique twist.
Make it Spicy: Add a pinch of red pepper flakes or a dash of hot sauce to give the dish a little heat.
Low-Carb Option: For a low-carb alternative, serve this casserole with a side of cauliflower rice instead of regular rice or pasta.
Dairy-Free: Substitute the cream cheese and sour cream with dairy-free alternatives such as cashew cream and vegan cheese.

How to Make the Recipe

Step 1: Preheat the Oven

Preheat your oven to 375°F (190°C).
Grease a 9×13 inch baking dish to prevent sticking.

Step 2: Season the Chicken

Season the boneless, skinless chicken breasts with salt, black pepper, paprika, and onion powder on both sides.
Heat olive oil in a skillet over medium-high heat.
Sear the chicken breasts for 2-3 minutes on each side, until golden brown.

Step 3: Prepare the Cream Cheese Mixture

In a bowl, mix the softened cream cheese, sour cream, minced garlic, and a pinch of salt until smooth and creamy.

Step 4: Assemble the Casserole

Layer the fresh spinach in the bottom of the prepared baking dish.
Place the seared chicken breasts on top of the spinach.
Spread the cream cheese mixture evenly over the chicken breasts.

Step 5: Add the Cheese

Sprinkle the shredded mozzarella cheese over the top of the casserole, covering it evenly.

Step 6: Bake the Casserole

Place the casserole in the preheated oven and bake for 25-30 minutes, or until the chicken is cooked through and the cheese is bubbly and golden brown.

Step 7: Serve and Enjoy

Let the casserole cool for 5 minutes before serving to allow the flavors to set.
Serve and enjoy the creamy, flavorful goodness!

Tips for Making the Recipe

Use Fresh Spinach: Fresh spinach works best in this recipe, but you can also use frozen spinach if that’s what you have on hand. Just be sure to thaw and drain it before using.
Sear the Chicken First: Searing the chicken adds flavor and helps it retain moisture while baking.
Check for Doneness: Use a meat thermometer to ensure the chicken has reached an internal temperature of 165°F (74°C) to guarantee it’s fully cooked.
Cream Cheese Texture: Ensure your cream cheese is softened before mixing to avoid lumps in the sauce.
Leftovers: This casserole stores well in the fridge for up to 3 days. Reheat it in the microwave or oven for a quick and easy meal.

How to Serve

This Chicken and Spinach Casserole pairs wonderfully with a simple side salad or roasted vegetables. You can also serve it with a side of mashed potatoes, rice, or quinoa for a heartier meal. For an extra burst of flavor, drizzle with a little balsamic glaze or top with fresh herbs like parsley or thyme.

Make Ahead and Storage

Storing Leftovers

Leftovers can be stored in an airtight container in the refrigerator for up to 3 days.
Reheat in the microwave or oven until heated through. If reheating in the oven, cover with foil to keep the chicken moist.

Freezing

You can freeze this casserole for up to 3 months. To freeze, let the casserole cool completely, then wrap it tightly in plastic wrap or aluminum foil.
When ready to eat, thaw in the refrigerator overnight and reheat in the oven at 375°F until heated through.

Reheating

Reheat individual portions in the microwave or heat the whole casserole in the oven at 350°F for about 15 minutes or until fully heated.

FAQs

1. Can I use chicken thighs instead of chicken breasts?

Yes, you can substitute chicken thighs for the chicken breasts. Just be sure to adjust the cooking time accordingly, as thighs may take a little longer to cook.

2. Can I use frozen spinach?

Yes, you can use frozen spinach, but be sure to thaw and drain it thoroughly before using to prevent excess water in the casserole.

3. Can I add other vegetables to the casserole?

Absolutely! Feel free to add other vegetables like mushrooms, zucchini, or bell peppers to the casserole for extra flavor and texture.

4. Can I make this casserole ahead of time?

Yes, you can prepare the casserole ahead of time by assembling it and refrigerating it until you’re ready to bake. Just bake it when you’re ready to eat.

5. How do I know when the chicken is fully cooked?

The chicken should reach an internal temperature of 165°F (74°C) to ensure it’s fully cooked. You can use a meat thermometer to check.

6. Can I use a different cheese?

Yes, you can substitute mozzarella with other cheeses like cheddar, Parmesan, or a blend of your favorites.

7. Can I make this casserole low-carb?

Yes, you can serve this casserole with cauliflower rice instead of regular rice or noodles for a low-carb version.

8. Can I freeze this casserole?

Yes, this casserole freezes well. Make sure to let it cool completely before wrapping it tightly for freezing.

9. Can I use Greek yogurt instead of sour cream?

Yes, Greek yogurt can be used as a healthier alternative to sour cream for a slight tangy flavor.

10. What should I serve with this casserole?

This casserole pairs well with a fresh salad, roasted vegetables, or mashed potatoes for a complete meal.

Conclusion

Chicken and Spinach Casserole with Cream Cheese is the perfect dish for anyone looking for a comforting, creamy, and easy-to-make dinner. Packed with tender chicken, nutritious spinach, and a rich cream cheese sauce, it’s a delicious and wholesome meal that the whole family will love. Whether you’re preparing it for a busy weeknight or a weekend gathering, this casserole is sure to impress.